Thermo Fisher Scientific RNF34 Polyclonal Antibody
Thermo Fisher Scientific의 RNF34 Polyclonal Antibody는 인간 RNF34 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot 및 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 항-아포토시스 연구 및 단백질 상호작용 분석에 활용 가능합니다.
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Thermo Fisher Scientific RNF34 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human RNF34. Recombinant protein control fragment (Product #RP-105587) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.16 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2664319 |
Product Specific Information
Immunogen sequence:
NIVCKACGLSF SVFRKKHVCC DCKKDFCSVC SVLQENLRRC STCHLLQETA FQRPQLMRLK VKDL
Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 97%
Target Information
The RNF34 gene encodes a protein containing a RINF finger motif, which mediates protein-protein and protein-DNA interactions. RNF34 interacts with DNAJA3/hTid-1, a DnaJ protein involved in apoptosis modulation. Overexpression in HeLa cells confers resistance to TNF-alpha-induced apoptosis, suggesting an anti-apoptotic role. RNF34 can be cleaved by caspase-3 during apoptosis induction. Alternatively spliced variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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