Thermo Fisher Scientific CPA6 Polyclonal Antibody
Thermo Fisher Scientific의 CPA6 폴리클로날 항체는 인간, 마우스, 랫트 시료에 반응하며 WB, IHC, ELISA에 적합합니다. Recombinant CPA6 단백질(aa130–437)을 면역원으로 사용하였고, 액상 형태로 -20°C에서 보관됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA589343
- 판매단위
- pk
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1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CPA6 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 130–437 of human CPA6 (NP_0650943) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.31 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805506 |
Product Specific Information
Immunogen sequence:
SLSGYNYEVY HSLEEIQNWM HHLNKTHSGL IHMFSIGRSY EGRSLFILKL GRRSRLKRAV WIDCGIHARE WIGPAFCQWF VKEALLTYKS DPAMRKMLNH LYFYIMPVFN VDGYHFSWTN DRFWRKTRSR NSRFRCRGVD ANRNWKVKWC DEGASMHPCD DTYCGPFPES EPEVKAVANF LRKHRKHIRA YLSFHAYAQM LLYPYSYKYA TIPNFRCVES AAYKAVNALQ SVYGVRYRYG PASTTLYVSS GSSMDWAYKN GIPYAFAFEL RDTGYFGFLL PEMLIKPTCT ETMLAVKNIT MHLLKKCP
Positive Samples: HT-29, HepG2, HeLa
Cellular Location: extracellular matrix, extracellular space
Target Information
Members of the M14 metallocarboxypeptidase protein family serve diverse functions and are divided into three subfamilies based on structure, function, and amino acid sequence similarity.
CPA6 (Carboxypeptidase A6) is a 437 amino acid secreted, zinc-binding protein containing a propetide at the amino terminus, cleaved upon activation. Expressed broadly in embryonic tissues, CPA6 is found at highest levels in the adult olfactory bulb and epididymis.
CPA6 cleaves large C-terminal hydrophobic residues from proteins and substrates, likely involved in extracellular neuropeptide processing. Mutations in CPA6 are linked to Duane syndrome, a congenital eye-movement disorder associated with abnormal cranial nerve VI development.
Three isoforms of CPA6 exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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