Thermo Fisher Scientific Desmoglein 1/2 Monoclonal Antibody (DG 3.10)
Desmoglein 1/2 단백질을 인식하는 Mouse Monoclonal Antibody(DG 3.10). Western blot, IHC, ICC 등 다양한 응용에 적합. Affinity chromatography로 정제된 액상 형태로, 4°C 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:4,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:100 | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DG 3.10 |
| Immunogen | Band 3 polypeptide of isolated desmosomes from bovine muzzle epidermis |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.5% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
DSG1 (Desmoglein 1)
Protein coding gene associated with diseases such as:
- Erythroderma, Congenital, With Palmoplantar Keratoderma, Hypotrichosis, And Hyper-IgE
- Palmoplantar Keratoderma I, Striate, Focal, Or Diffuse
Related pathways: Keratinization, Apoptotic execution phase
Gene Ontology (GO): Calcium ion binding, toxic substance binding
Paralog: DSG4
DSG2 (Desmoglein 2)
Protein coding gene associated with:
- Arrhythmogenic Right Ventricular Dysplasia, Familial, 10
- Cardiomyopathy, Dilated, 1Bb
Related pathways: Keratinization, Apoptotic execution phase
Gene Ontology (GO): Calcium ion binding, cell adhesive protein binding involved in bundle of His cell–Purkinje myocyte communication
Paralog: DSG4
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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