Thermo Fisher Scientific Desmoglein 1/2 Monoclonal Antibody (DG 3.10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:4,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:10-1:100

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Species Reactivity

Bovine, Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

DG 3.10

Immunogen

Band 3 polypeptide of isolated desmosomes from bovine muzzle epidermis if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Desmoglein 1/2,uniProtId:Q03763-1,ncbiNodeId:9913,antigenRange:1-1043,antigenLength:1043,antigenImageFileName:690002-1ML_Desmoglein_12_Q03763-1_House_mouse.svg,antigenImageFileNamePDP:690002-1ML_Desmoglein_12_Q03763-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 0.5% BSA

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

DSG1 (Desmoglein 1) is a Protein Coding gene. Diseases associated with DSG1 include Erythroderma, Congenital, With Palmoplantar Keratoderma, Hypotrichosis, And Hyper-Ige and Palmoplantar Keratoderma I, Striate, Focal, Or Diffuse. Among its related pathways are Keratinization and Apoptotic execution phase. Gene Ontology (GO) annotations related to this gene include calcium ion binding and toxic substance binding. An important paralog of this gene is DSG4. DSG2 (Desmoglein 2) is a Protein Coding gene. Diseases associated with DSG2 include Arrhythmogenic Right Ventricular Dysplasia, Familial, 10 and Cardiomyopathy, Dilated, 1Bb. Among its related pathways are Keratinization and Apoptotic execution phase. Gene Ontology (GO) annotations related to this gene include calcium ion binding and cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication. An important paralog of this gene is DSG4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.