Thermo Fisher Scientific CKAP4 Polyclonal Antibody
CKAP4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, 인간 및 마우스 반응성. 연구용으로만 사용.
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Thermo Fisher Scientific CKAP4 Polyclonal Antibody
Applications
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 3–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 552 and 602 of human cytoskeleton-associated protein 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene encodes the coiled-coil containing protein optineurin, which may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma.
Optineurin interacts with adenovirus E3-14.7K protein and may utilize TNF-α or Fas-ligand pathways to mediate apoptosis, inflammation, or vasoconstriction.
It may also function in cellular morphogenesis, membrane trafficking, vesicle trafficking, and transcription activation through interactions with RAB8, huntingtin, and transcription factor IIIA proteins.
Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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