Thermo Fisher Scientific Opticin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the C-terminal of human OPTC (aa 254-303). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Opticin,uniProtId:Q9UBM4-1,ncbiNodeId:9606,antigenRange:254-303,antigenLength:332,antigenImageFileName:PA5-44262_Opticin_Q9UBM4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-44262_Opticin_Q9UBM4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2576769

Product Specific Information

Peptide sequence: LSDNLLDSIP GPLPLSLRSV HLQNNLIETM QRDVFCDPEE HKHTRRQLED

Sequence homology: Cow: 77%; Dog: 100%; Guinea Pig: 85%; Horse: 92%; Human: 100%; Mouse: 85%; Pig: 100%; Rabbit: 92%; Rat: 100%; Zebrafish: 83%

Target Information

Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.