Thermo Fisher Scientific Phospho-TAK1 (Thr187) Polyclonal Antibody
Phospho-TAK1 (Thr187) 특이적 항체로, 인산화된 TAK1 단백질 검출에 적합합니다. Western blot, IHC, ICC 등 다양한 응용 가능. Rabbit polyclonal IgG 형식이며 1 mg/mL 농도의 액상 제품입니다. -20°C에서 보관하며 연구용으로만 사용됩니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TAK1 around the phosphorylation site of Thr187. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903029 |
Target Information
TAK1 (also known as MAP3K7) is a serine/threonine kinase involved in multiple signaling pathways. Initially identified as a TGF-β-activated kinase, TAK1 interacts with TGF-β receptor and TRAF6 to modulate activation of JNK and p38. It also participates in Wnt, BMP, and activin signaling, as well as responses to thyroid hormone, osmotic stress, endothelin, and ephrine.
Through activation of von Hippel-Lindau tumor suppressor expression, TAK1 represses PDGF-B, integrin β1, and integrin β5, facilitating proper wound healing. TAK1 is essential for IKK activation in pathways including IL-1, IL-6, IL-18, TNF, CD40, TLR, and RIG-I. Activation of the TAK1-IKK pathway requires TAB2/3 and ubiquitination, during which TAK1 is autophosphorylated at Thr178, Thr184, Thr187, and Ser192 before phosphorylating IKK-β. TAK1 also represses human telomerase reverse transcriptase, indicating a role in regulating cell lifespan.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-CHK2 (Thr383) Polyclonal Antibody
717,600원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-FOXO3A (Ser253) Polyclonal Antibody
655,000원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-TAK1 (Thr187) Polyclonal Antibody
673,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-PDPK1 (Ser241) Polyclonal Antibody
673,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-Tau (Ser202) Polyclonal Antibody
717,600원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|