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Thermo Fisher Scientific CISD2 Monoclonal Antibody (OTI4D12)
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CISD2 단백질을 인식하는 마우스 단클론 항체로 Western blot 및 IHC(P) 검증됨. 인간 시료에 반응하며, 1 mg/mL 농도의 액상 비접합 형태. PBS 기반 완충액에 보관하며, -20°C에서 보관 권장. 연구용으로만 사용 가능.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오전 06:43
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Thermo Fisher Scientific MA527296 CISD2 Monoclonal Antibody (OTI4D12) 100 ul pk판매 단위 pk ·
재고 확인 필요
775,200원VAT 포함 852,720원
Thermo Fisher Scientific · Thermo Fisher Scientific CISD2 Monoclonal Antibody (OTI4D12)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D12 |
| Immunogen | Full length human recombinant protein of CISD2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724147 |
Target Information
Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are associated with the neurodegenerative disorder Wolfram syndrome 2. CISD2 is a zinc finger protein localized to the endoplasmic reticulum and mitochondria, binding an iron/sulfur cluster. It interacts with Bcl-2 and can be displaced by the BH3-only protein BIK, contributing to the regulation of BIK-initiated autophagy. CISD2 deficiency in mice causes mitochondrial breakdown, autophagic cell death, and premature aging phenotypes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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