Thermo Fisher Scientific HKR1 Polyclonal Antibody
Human HKR1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC에 검증됨. 합성 펩타이드 면역원으로 제작되었으며, 고순도 Affinity Chromatography 정제. 액상 형태로 -20°C 보관, 연구용으로만 사용 가능.
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Thermo Fisher Scientific HKR1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.125 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human HKR1 (aa 610–659) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609548 |
Product Specific Information
Peptide Sequence:
RECGQGFSRQ SHLIRHQRTH SGEKPYICRK CGRGFSRKSN LIRHQRTHSG
Sequence Homology:
Cow: 100%
Dog: 100%
Guinea Pig: 92%
Horse: 100%
Human: 100%
Mouse: 100%
Pig: 100%
Rabbit: 86%
Rat: 100%
Target Information
Zinc-finger proteins contain DNA-binding domains and have diverse functions, primarily related to transcriptional activation or repression. Most zinc-finger proteins possess a Kruppel-type DNA binding domain and a KRAB domain, which interacts with KAP1 to recruit histone-modifying proteins.
HKR1 (Krueppel-related zinc finger protein 1 or zinc finger protein 875) is a 659 amino acid nuclear protein involved in transcriptional regulation. It exists as two alternatively spliced isoforms and belongs to the Krueppel C2H2-type zinc-finger protein family, containing thirteen C2H2-type zinc fingers and one KRAB domain. The HKR1 gene maps to human chromosome 19q13.12.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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