Thermo Fisher Scientific PTHLH Polyclonal Antibody
PTHLH 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 적합합니다. Human 및 Mouse 시료에서 검증되었으며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–8 µg/mL | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | - | View 1 publication |
Product Specifications
| Category | Specification |
|---|---|
| Published species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human PTHLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2609473 |
Product Specific Information
Peptide sequence:
YKEQPLKTPG KKKKGKPGKR KEQEKKKRRT RSAWLDSGVT GSGLEGDHLS
Sequence homology:
Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%
Target Information
The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is involved in lactation, possibly by regulating calcium mobilization and transfer to milk. The receptor PTHR1 is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG start sites, giving rise to nuclear forms of this hormone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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