Thermo Fisher Scientific Cdc37 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CDC37 protein for Western blot applications. High specificity and affinity purified via antigen chromatography. Supplied as liquid form, unconjugated, with glycerol for stability. Suitable for research use only.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CDC37 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.97 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735619 |
Product Specific Information
- Positive Control: Jurkat, Raji, NCI-H929
- Predicted Reactivity: Mouse (95%), Rat (90%), Pig (97%), Chicken (85%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
In S. cerevisiae, Cdc37 is an important regulator of the cell division cycle through its action on cyclin-dependent kinases (CDKs). It is also associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase, and the sevenless receptor tyrosine kinase.
Cdc37 is the same protein previously described as p50, found complexed with Src-family kinases (Fyn, Yes, Fes, Lck, Fgr), Raf, and pp60v-src. It functions as a chaperone both independently and in concert with HSP90, and is necessary for the binding of HSP90 to Cdk4.
주의사항
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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