Thermo Fisher Scientific SRY Monoclonal Antibody (OTI3C8), TrueMAB
SRY 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 Immunocytochemistry에 적합합니다. Human 시료에 반응하며, 동결건조 형태로 제공됩니다. 재구성 후 약 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:2,000
- Immunocytochemistry (ICC/IF): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C8 |
| Immunogen | Full length human recombinant protein of human SRY produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This intronless gene encodes a transcription factor belonging to the high mobility group (HMG)-box family of DNA-binding proteins.
The SRY protein acts as the testis-determining factor (TDF), initiating male sex determination.
Mutations in this gene can result in XY females with gonadal dysgenesis (Swyer syndrome), while translocation of the Y chromosome region containing this gene to the X chromosome can cause XX male syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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