Thermo Fisher Scientific SRY Monoclonal Antibody (OTI3C8), TrueMAB

Applications

• Western Blot (WB): 1:2,000
• Immunocytochemistry (ICC/IF): 1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

This intronless gene encodes a transcription factor belonging to the high mobility group (HMG)-box family of DNA-binding proteins.
The SRY protein acts as the testis-determining factor (TDF), initiating male sex determination.
Mutations in this gene can result in XY females with gonadal dysgenesis (Swyer syndrome), while translocation of the Y chromosome region containing this gene to the X chromosome can cause XX male syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.