Thermo Fisher Scientific NAGPA Polyclonal Antibody
Human NAGPA 단백질의 N-말단 영역을 타겟으로 하는 Rabbit Polyclonal Antibody. Western blot에 적합하며, 0.5 mg/mL 농도의 액상 형태로 제공. PBS 및 sucrose buffer에 보관하며 -20°C 저장 권장. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human NAGPA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690979 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 86%
Target Information
Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network.
This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases.
Commonly known as uncovering enzyme (UCE), this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties, producing the recognition marker.
The encoded preproprotein is proteolytically processed by furin to generate the mature enzyme, a homotetramer of two disulfide-linked homodimers.
Mutations in this gene are associated with developmental stuttering in human patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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