Thermo Fisher Scientific NOD4 Polyclonal Antibody
인간 NOD4 단백질을 인식하는 Rabbit Polyclonal Antibody로, 면역세포 내 선천 면역 반응 연구에 적합합니다. ICC/IF 실험에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 장기 보관 시 -20°C에서 냉동 보관을 권장합니다.
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Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NOD4. Recombinant protein control fragment (Product #RP-106918) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663913 |
Product Specific Information
Immunogen sequence:
GLVRCFSTLQW LFRLDISFES QHILLRGDKT SRDMWATGSL PDFPAAAKFL GFRQRCIPRS LCLSECPLEP PSLTRLCATL KDCPGPLELQ LSCEFLSDQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 55%
- Rat: 50%
Target Information
NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins involved in innate immune defense.
NOD4 contains a CARD-like domain, a central NOD domain, and a large LRR region.
It is an IFN-gamma-inducible nuclear protein that plays a role in homeostatic control of innate immunity and antiviral defense mechanisms.
As a key negative regulator of NF-kappa-B and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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