Thermo Fisher Scientific USP6 Polyclonal Antibody
Thermo Fisher Scientific의 USP6 Polyclonal Antibody는 인간 USP6 단백질을 인식하는 염소 유래 다클론 항체입니다. ICC/IF 및 유세포분석에 적합하며, USP32 및 TBC1D3 단백질과 교차 반응하지 않습니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
- 카탈로그번호
- PA5142888
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-HHIDLDVRTTLRNH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933531 |
Product Specific Information
- This antibody is expected not to cross-react with USP32 or TBC1D3 proteins.
- Tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
- Preliminary analysis showed no signal in Western Blot.
Target Information
USP6 is a deubiquitinase with ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoform2 (but not isoform3) shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It can initiate tumorigenesis by inducing matrix metalloproteinase production following NF-kappa-B activation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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