Thermo Fisher Scientific Melanophilin Polyclonal Antibody
Melanophilin 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot, ICC/IF, GST pull down 등 다양한 응용 가능. Mouse 반응성, Goat 유래 IgG. 고순도, 액상 형태로 -20°C에서 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.1–1.0 µg/mL |
| GST Pull Down (GPD) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (ARHIFAKPVMAQQP) corresponding to the C-terminus amino acids of Mlph (aa 577–590) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980621 |
Product Specific Information
- Predicted to react with rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
Slac2-a (synaptotagmin-like protein homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes.
It binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), located near the N-terminus.
Transport of pigment and cytotoxic granules in melanocytes requires stable formation of this complex.
Mutations in the binding domains of these proteins may cause albinism and/or severe immune disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-18050_Melanophilin_Q91V27-1_Goat.svg, PA5-18050_Melanophilin_Q91V27-1_Goat_PDP.jpeg)
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