
ELK Biotechnology RM43 rabbit pAb
RM43 rabbit pAb는 인간, 랫, 마우스 시료에 반응하는 폴리클로날 항체로, WB 및 ELISA에 사용됩니다. 인간 단백질 유래 펩타이드로 면역화되었으며, 미토콘드리아 단백질 분석에 적합합니다. 고농도(1 mg/ml)로 안정적이며 -20°C에서 1년 보관 가능합니다.
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제품명
RM43 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human protein (AA range: 120–200) |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 23 kD |
| GeneID (Human) | 84545 |
| Human Swiss-Prot No | Q8N983 |
| Cellular Localization | Mitochondrion |
| Species Reactivity | Human; Rat; Mouse |
| Storage | -20°C / 1 year |
| Host | Rabbit |
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and participate in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition—opposite to prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins of the mitoribosome vary significantly among species, affecting sequence and biochemical properties. This gene encodes a 39S subunit protein and overlaps with the semaphorin class 4 protein gene (SEMA4G) at map location 10q24.31, transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding distinct isoforms.
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