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ELK Biotechnology PER1 rabbit pAb
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ELK Biotechnology PER1 rabbit pAb

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PER1 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 인간, 생쥐, 랫드 시료에 반응하며 핵 및 세포질에 발현된 PER1 단백질 검출에 사용됩니다. 냉동 보관(-20°C) 시 1년 안정적으로 유지됩니다.

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pk
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ELK Biotechnology ES9274-100UL PER1 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES9274-50UL PER1 rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology PER1 rabbit pAb

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PER1 rabbit pAb

제품 정보

항목 내용
Applications WB; ELISA
Recommended Dilutions WB 1:500–2000, ELISA 1:5000–20000
Immunogen Synthesized peptide derived from human protein (AA range: 1110–1190)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 141 kD
Gene ID (Human) 5187
Human Swiss-Prot No O15534
Cellular Localization Nucleus, Cytoplasm. Nucleocytoplasmic shuttling occurs via interactions with circadian core oscillator proteins and phosphorylation. PER1 retention in the cytoplasm occurs through PER1–PER2 heterodimer formation. Translocates to the nucleus after phosphorylation by CSNK1D or CSNK1E, or by CRY1/CRY2 interaction (By similarity).
Species Reactivity Human; Mouse; Rat

Background

This gene belongs to the Period family and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. It encodes components involved in circadian rhythms of locomotor activity, metabolism, and behavior. Upregulated by CLOCK/ARNTL heterodimers, it represses this activation via PER/CRY heterodimers interacting with CLOCK/ARNTL. Polymorphisms in this gene may increase cancer risk. Alternative splicing has been observed but not fully characterized.
[Provided by RefSeq, Jan 2014]

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