Thermo Fisher Scientific CD16b VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1310)
Thermo Fisher의 CD16b VHH-8His-Cys-tag 항체는 알파카 유래 리콤비넌트 단일클론 항체로, 인간 CD16b(FcγRIIIb)를 인식합니다. CHO 세포에서 발현되며 ELISA에 적합합니다. Metal-chelate chromatography로 정제되었고, PBS 용액 내 1 mg/mL 농도로 제공됩니다.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1310 |
| Immunogen | Recombinant Human CD16b/FCGR3B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
CD16 (FCGR3A) is a 50–65 kDa cell surface molecule that exists in two forms: a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol-linked form expressed by granulocytes.
CD16 is a low-affinity receptor for IgG (FcR III) and plays a key role in antibody-dependent cellular cytotoxicity (ADCC) mediated by NK cells.
Human CD16 is expressed in two isoforms, FCGR3A and FCGR3B. FCGR3A associates with the FcepsilonRI-gamma subunit and mediates NK cell cytotoxicity, while FCGR3B is a GPI-linked monomeric receptor on neutrophils involved in activation and adhesion.
Dysfunction of CD16 is associated with diseases such as immunodeficiency 20 and systemic lupus erythematosus.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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