Thermo Fisher Scientific FGG Monoclonal Antibody (OTI2D2), TrueMAB
FGG 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(Paraffin)에 적합. Human 및 Mouse 시료에 반응하며, 1 mg/mL 농도의 액상 형태로 제공. Affinity chromatography로 정제되었으며, -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:400–1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D2 |
| Immunogen | Full length human recombinant protein of human FGG produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the most abundant component of blood clots. Various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and act as mitogens for several cell types. Mutations in this gene can lead to disorders such as dysfibrinogenemia, hypofibrinogenemia, and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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