Thermo Fisher Scientific IDH1 Monoclonal Antibody (4A3)
IDH1 단백질을 인식하는 Thermo Fisher Scientific의 4A3 단클론 항체. Western blot 및 IHC(Paraffin) 실험에 적합하며, 인간 및 제브라피시에 반응. Protein A로 정제된 액상 항체로 1 mg/mL 농도, PBS 버퍼(50% 글리세롤, 0.02% 아지드) 내 저장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Zebrafish |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4A3 |
| Immunogen | Recombinant protein corresponding to a region of IDH1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2717315 |
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one utilizing NAD(+) and the other NADP(+) as electron acceptors. Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent enzymes localized in the mitochondrial matrix, and two NADP(+)-dependent enzymes, one mitochondrial and the other predominantly cytosolic. The cytoplasmic NADP(+)-dependent enzyme, encoded by this gene, is also found in peroxisomes and contains a PTS-1 peroxisomal targeting signal sequence. It plays a role in regenerating NADPH for peroxisomal reductions and in cytoplasmic NADPH production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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