Thermo Fisher Scientific SRPX2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 166-465 of human SRPX2 (NP_0552821) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SRPX2,uniProtId:O60687-1,ncbiNodeId:9606,antigenRange:166-465,antigenLength:465,antigenImageFileName:PA5-90463_SRPX2_O60687-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90463_SRPX2_O60687-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806088

Product Specific Information

Immunogen sequence: DGRWSGGEPV CVDIDPPKIR CPHSREKMAE PEKLTARVYW DPPLVKDSAD GTITRVTLRG PEPGSHFPEG EHVIRYTAYD RAYNRASCKF IVKVQVRRCP TLKPPQHGYL TCTSAGDNYG ATCEYHCDGG YDRQGTPSRV CQSSRQWSGS PPICAPMKIN VNVNSAAGLL DQFYEKQRLL IISAPDPSNR YYKMQISMLQ QSTCGLDLRH VTIIELVGQP PQEVGRIREQ QLSANIIEEL RQFQRLTRSY FNMVLIDKQG IDRDRYMEPV TPEEIFTFID DYLLSNQELT QRREQRDICE; Positive Samples: Mouse brain; Cellular Location: Cell junction, Cell surface, Cytoplasm, synapse

Target Information

Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.