Thermo Fisher Scientific KPNA2 Recombinant Rabbit Monoclonal Antibody (23GB6295)
KPNA2 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot과 유세포분석에 적합합니다. HEK293F 시스템에서 발현되었으며, 친화 크로마토그래피로 정제되었습니다. 인간, 생쥐, 랫트 시료에 반응하며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB6295 |
| Immunogen | A synthesized peptide derived from human KPNA2 (50–100AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The import of proteins into the nucleus involves at least two steps:
- An energy-independent docking of the protein to the nuclear envelope.
- An energy-dependent translocation through the nuclear pore complex.
Imported proteins require a nuclear localization sequence (NLS), typically a short region of basic amino acids or two such regions spaced about 10 amino acids apart.
Proteins involved in the first step of nuclear import include Xenopus importin and its yeast homolog SRP1, which bind to the NLS.
KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins.
Additionally, KPNA2 may play a role in VJ recombination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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