Thermo Fisher Scientific ATP11B Polyclonal Antibody
Thermo Fisher Scientific의 ATP11B Polyclonal Antibody는 인간 ATP11B 단백질의 N말단 펩타이드(aa 144-193)를 표적으로 하는 토끼 유래 IgG 항체입니다. Western blot에 적합하며, 액상 형태로 공급됩니다. 높은 종 간 상동성과 안정적인 보관 조건을 제공합니다.
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Applications
- Western Blot (WB)
Tested Dilution
- 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human ATP11B (aa 144–193) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884347 |
Product Specific Information
- Immunogen sequence: DIVRIAKDEI FPADLVLLSS DRLDGSCHVT TASLDGETNL KTHVAVPETA
- Storage recommendations:
- Short term: 2–8°C (up to 1 week)
- Long term: -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology:
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%
Target Information
ATP11B is a widely expressed integral membrane ATPase thought to drive phospholipid transport across membranes. It may be hormonally regulated and involved in subnuclear trafficking of transcription factors with RING motifs. While its exact substrate is unknown, increased ATP11A expression has been linked to resistance against anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting ATP11B may contribute to cell survival under stress conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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