Thermo Fisher Scientific PNUTS Polyclonal Antibody

Applications

Immunohistochemistry (IHC)

• Tested Dilution: 1:100–1:500

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, predicted to react with Rat, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Small-eared galago, and Crab-eating macaque

Target Information

RNA polymerases transcribe nuclear genes for ribosomal RNA, representing ribosomal biogenesis.
RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes coding for large ribosomal RNA.
Different subunits of the Pol I transcription machinery are regulated by various physiological stimuli, suggesting multiple signaling pathways are involved.
RPA40 and RPA16 are Pol I subunits that associate early in RNA polymerase I assembly.
RPA40 is essential for the integrity of the complex and is also a subunit of RNA polymerase III (Pol III).
RPA40, RPA16, and RPA135 encode three subunits of RNA polymerase I, while RPA194 is the largest subunit and is not part of Pol II or Pol III.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.