Thermo Fisher Scientific CYB5R3 Monoclonal Antibody (2A9)

Applications

Tested Dilution

Publications

ELISA (ELISA)

1 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

2A9

Immunogen

CYB5R3 (AAH04821.1, 157 a.a. approximately 252 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CYB5R3,uniProtId:P00387-1,ncbiNodeId:9606,antigenRange:157-252,antigenLength:301,antigenImageFileName:H00001727-M01_CYB5R3_P00387-1_House_mouse.svg,antigenImageFileNamePDP:H00001727-M01_CYB5R3_P00387-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: FAIRPDKKSN PIIRTVKSVG MIAGGTGITP MLQVIRAIMK DPDDHTVCHL LFANQTEKDI LLRPELEELR NKHSARFKLW YTLDRAPEAW DYGQGF

Target Information

CYB5R3 (NADH-cytochrome b5, reductase 3, diaphorase 1) is a 301 amino acid protein encoded by the human gene CYB5R3. CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms. Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane, while isoform 2 is the soluble form found in erythrocytes. CYB5R3 is involved in the desaturation and elongation of fatty acids, cholesterol biosynthesis,drug metabolism and, in erythrocytes, methemoglobin reduction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.