Thermo Fisher Scientific SCAMP2 Monoclonal Antibody (OTI2F3), TrueMAB
SCAMP2 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 버퍼에 보관되며 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:4,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F3 |
| Immunogen | Full length human recombinant protein of human SCAMP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Secretory carrier membrane proteins (SCAMPs) are components of post-Golgi membranes involved in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments responsible for recycling of cell surface receptors and endocytosis. In neurons, SCAMPs associate with synaptic vesicles, secretion granules, and transporter vesicles.
SCAMPs possess four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1–3 contain cytoplasmic N-terminal regions with NPF repeats, which interact with EH domain proteins functioning in vesicle budding from the plasma membrane or Golgi complex. SCAMPs 4 and 5 lack these NPF repeats. SCAMPs 1–4 are ubiquitously expressed, while SCAMP 5 is brain-specific and expressed late in development, coinciding with mature synapse expansion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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