Thermo Fisher Scientific PDZRN3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PDZRN3. Validated for ICC/IF applications. Supplied unconjugated in liquid form with antigen affinity purification. Ideal for studying E3 ubiquitin-protein ligase function and MUSK regulation. For research use...
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PDZRN3 (Control fragment: Product #RP-107064) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2665175 |
Product Specific Information
Immunogen sequence:
SEQENNGDDAT ASSNPLAGQR KLTCSQDTLG SGDLPFSNES FISADCTDAD YLGIPVDECE RFR
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 95%
Target Information
E3 ubiquitin-protein ligase PDZRN3 plays an important role in regulating the surface level of MUSK on myotubes.
It mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation.
May contribute to terminal myogenic differentiation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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