Thermo Fisher Scientific Nkx6.1 Polyclonal Antibody
Human Nkx6.1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. β세포 및 중추신경계 연구용으로 적합하며, 4°C 또는 -20°C에서 안정적으로 보관 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Nkx6.1. Recombinant protein control fragment (Product #RP-97603) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644708 |
Product Specific Information
- Immunogen sequence: PLGTHNPGGL KPPATGGLSS LGSPPQQLSA ATPHGINDIL SRPSM
- Highest antigen sequence identity to orthologs: Mouse – 96%, Rat – 96%
Target Information
NKX6.1 is a bi-functional transcription factor involved in both the central nervous system and pancreatic function. It regulates gene expression and repression, contributing to the formation of motoneurons, oligodendrocytes, and insulin-secreting beta cells. NKX6.1 interacts with Pax6 and Pdx-1 near its homeobox DNA-binding domain. It is a key target for diabetes and neurological disease research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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