Thermo Fisher Scientific Rho Pan Polyclonal Antibody
Rho 단백질에 특이적인 폴리클로날 항체로, Western blot 및 IHC에 적합. Rabbit IgG 유래로 합성 펩타이드를 면역원으로 사용. 세포 골격 재구성과 신호전달 연구에 활용 가능. 4°C 또는 -20°C에서 안정적으로 보관 가능.
- 카탈로그번호
- OSC00025W
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Rho-related GTP-binding proteins (RhOA, RhOB, RhOC, RhOF, RhOQ) and RAC1, RAC2, RAC3, CDC42 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10984173 |
Product Specific Information
- Glycerol (1:1) may be added for additional stability.
- The peptide is homologous in many other species.
Target Information
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades.
Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility.
The protein encoded by this gene is prenylated at its C-terminus and localizes to the cytoplasm and plasma membrane.
It is important in cell locomotion, and overexpression is associated with tumor cell proliferation and metastasis.
Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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