Thermo Fisher Scientific GTF2B Monoclonal Antibody (OTI1H10), TrueMAB
인간 GTF2B 단백질(아미노산 43-316)을 인식하는 Mouse IgG1 단클론 항체. Western blot에 1:2,000 희석으로 사용 가능. 액상 형태, 1 mg/mL 농도, 친화 크로마토그래피 정제. 연구용 한정, 진단용 불가.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 43–316 of human GTF2B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ubiquitin is a 76 amino acid highly conserved eukaryotic polypeptide that selectively marks cellular proteins for proteolytic degradation by the 26S proteasome. This process regulates concentrations of key regulatory proteins by limiting their lifespans. Polyubiquitination involves activation of ubiquitin by E1 enzyme, transfer to E2, and covalent linkage to target proteins directly or via E3 ligase. Deubiquitination enzymes reverse this marking. Posttranslational tagging by ubiquitin influences numerous cellular processes including:
- Cell cycle and growth
- Differentiation and embryogenesis
- Apoptosis and signal transduction
- DNA repair and replication
- Transmembrane transport
- Stress responses and immune function
- Nervous system processes
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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