Thermo Fisher Scientific BCAS1/NABC1 Polyclonal Antibody
BCAS1/NABC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, 연구용으로 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human BCAS1 (amino acids 542–584) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
BCAS1 was identified through positional cloning and found to be overexpressed in most breast cancer cell lines. It is cytoplasmically localized and likely forms homodimers via coiled-coil structures. High BCAS1 mRNA expression is observed in brain and prostate tissues, with lower levels in colon, intestine, and testis. Overexpression does not alter anchorage-dependent growth, indicating BCAS1 is not a typical oncogene. Amplification has also been observed in pancreatic carcinoma, suggesting a role in cell proliferation control.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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