Thermo Fisher Scientific BAIAP2 Polyclonal Antibody
BAIAP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. WB, IHC, ICC, ELISA 등 다양한 응용에 적합하며, Human, Mouse, Rat 시료에 반응합니다. 고순도 Protein A 정제 및 안정한 액상 형태로 연구용에 최적화되어 있습니다.
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Thermo Fisher Scientific BAIAP2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human IRS P53, amino acids 151–250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane-bound G-proteins to cytoplasmic effector proteins. It functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is involved in the formation of stress fibers and cytokinesis. The protein participates in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. Additionally, it interacts with the dentatorubral-pallidoluysian atrophy gene, associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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