Thermo Fisher Scientific BAIAP2 Polyclonal Antibody

Thermo Fisher Scientific BAIAP2 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Target Information

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane-bound G-proteins to cytoplasmic effector proteins. It functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is involved in the formation of stress fibers and cytokinesis. The protein participates in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. Additionally, it interacts with the dentatorubral-pallidoluysian atrophy gene, associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.