Thermo Fisher Scientific Tensin 3 Polyclonal Antibody
Tensin 3 단백질을 인식하는 Rabbit Polyclonal 항체로 Western Blot에 적합합니다. Mouse 시료에 반응하며, 고순도의 Affinity chromatography 정제 제품입니다. PBS + 2% sucrose buffer에 보존되며, -20°C에서 보관 권장됩니다.
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of mouse Tensin 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689804 |
Product Specific Information
This target displays homology in the following species:
Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Target Information
The Tensin (Tns) family of proteins is involved in maintaining cellular structure by anchoring actin filaments at focal adhesions via F-actin binding and capping activities. Tns proteins contain a Src homology 2 (SH2) domain and can be phosphorylated, suggesting a role in signal transduction cascades. These characteristics indicate that Tns proteins may link the cytoskeleton and signal transduction pathways.
Tns3, also known as TEM6 or TENS1, localizes to the focal adhesions of the plasma membrane. It is predominantly expressed in thyroid and placenta but also found in heart, liver, brain, prostate, pancreas, kidney, lung, skeletal muscle, and white blood cells. Tns3 is essential for proper growth and development, as shown by growth retardation and death in Tns3-/- mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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