Thermo Fisher Scientific alpha Adducin Monoclonal Antibody (5D4H1)
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인간 alpha Adducin 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, WB, IHC, ELISA에 적합합니다. 1 mg/mL 농도의 액상 형태이며 Protein G로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific alpha Adducin Monoclonal Antibody (5D4H1)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5D4H1 |
| Immunogen | Purified recombinant fragment of human ADD1 (aa: 1–193) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898354 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein consisting of related subunits produced from distinct genes but sharing similar structure.
- Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region.
- Alpha- and gamma-adducins are ubiquitously expressed, while beta-adducin is highly expressed in brain and hematopoietic tissues.
- Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.
- Alternative splicing produces multiple variants encoding distinct isoforms; not all variants have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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