Thermo Fisher Scientific ERVW-1 Polyclonal Antibody, Biotin
ERVW-1 단백질을 인식하는 Biotin 결합 폴리클로날 항체. Western blot, ELISA, IP에 적합. Human 시료 반응성, Rabbit 유래 IgG. 항원 친화 크로마토그래피로 정제, 안정적인 액상 형태로 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| ELISA | 1:50,000 |
| Immunoprecipitation (IP) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 480–538 of human ERVW-1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Proprietary buffer with 30% glycerol |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C for short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
HERVs are a class of multiple sclerosis–associated retroviruses. This antibody reacts with a replication-competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is derived from the virus envelope polyprotein sequence.
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have retained, lost, or modified their original functions during evolution. The HERVW endogenous envelope protein maintains fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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