Thermo Fisher Scientific DNAJB4 Polyclonal Antibody
DNAJB4 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원 사용, 1 mg/mL 농도. PBS/glycerol buffer에 보관하며 -20°C에서 저장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DNAJB4 (Accession Q9UDY4), corresponding to amino acid residues A100–G150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854229 |
Product Specific Information
Antibody detects endogenous levels of total DNAJB4.
Target Information
DnaJ heat shock induced proteins, originally identified in Escherichia coli, are regulated by the htpR protein. They play a critical role in the HSP70 chaperone system by interacting with HSP70 to stimulate ATP hydrolysis. These proteins contain cysteine-rich zinc finger regions forming peptide-binding domains essential for chaperone function.
DnaJB4 (DnaJ homolog subfamily B member 4), also known as HLJ1, is expressed in skeletal muscle, heart, and pancreas, with lower expression in brain, placenta, and liver. It is involved in protein degradation, exocytosis, and endocytosis regulation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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