Thermo Fisher Scientific TCTEX1D4 Polyclonal Antibody
TCTEX1D4 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB 및 IHC에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 연구용으로 적합.
- 카탈로그번호
- PA534447
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 19 amino acid synthetic peptide near the amino terminus of human TCTEX1D4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Refrigerated at 2–8°C for up to 3 months; store at -20°C for long-term storage |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551799 |
Product Specific Information
A suggested positive control is mouse liver tissue lysate.
PA5-34447 can be used with blocking peptide PEP-1489.
Target Information
Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting ATP into mechanical movement. Cytoplasmic or axonemal Dynein consists of approximately 12 subunits, including heavy chains, intermediate chains, and light chains, and plays essential roles in organelle transport and centrosome assembly.
TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D4, also called TCTEX2 beta, interacts with members of the TGF-beta receptor family and, when overexpressed, inhibits TGF-beta signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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