Thermo Fisher Scientific AMPK alpha-2 Monoclonal Antibody (206CT5.4.2)
AMPK alpha-2 단백질을 인식하는 Thermo Fisher Scientific의 mouse monoclonal antibody. Western blot 및 immunocytochemistry에 최적화. Human에 반응하며, Protein G 정제 및 PBS buffer에 보관. 에너지 대사 연구용으로 적합.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:25
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 206CT5.4.2 |
| Immunogen | PRKAA2 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897433 |
Target Information
The protein encoded by this gene is a catalytic subunit of AMP-activated protein kinase (AMPK).
AMPK is a heterotrimer consisting of an alpha catalytic subunit and non-catalytic beta and gamma subunits.
It is an important energy-sensing enzyme that monitors cellular energy status. In response to metabolic stress, AMPK is activated and phosphorylates acetyl-CoA carboxylase (ACC) and HMG-CoA reductase (HMGCR), key enzymes regulating fatty acid and cholesterol biosynthesis.
Studies suggest that this catalytic subunit may control insulin sensitivity and maintain myocardial energy homeostasis during ischemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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