Thermo Fisher Scientific HSPB8 Monoclonal Antibody (5D7)
HSPB8 단백질을 인식하는 Mouse monoclonal antibody (Clone 5D7). Western blot 및 ELISA에 적합하며, 고순도의 Affinity chromatography 정제 제품. 인간 시료 반응성, PBS buffer 보관, 연구용 전용.
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- H00026353-M02
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5D7 |
| Immunogen | HSPB8 (NP_055180, 97 a.a. ~196 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KVCVNVHSFK PEELMVKTKD GYVEVSGKHE EKQQEGGIVS KNFTKKIQLP AEVDPVTVFA SLSPEGLLII EAPQVPPYST FGESSFNNEL PQDSQEVTCT
Target Information
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conserved alpha-crystallin domain at the C-terminal part of the molecule.
Expression of this gene is induced by estrogen in estrogen receptor-positive breast cancer cells.
This protein functions as a chaperone in association with Bag3, a stimulator of macroautophagy.
It is involved in regulation of cell proliferation, apoptosis, and carcinogenesis.
Mutations in this gene have been associated with various neuromuscular diseases, including Charcot-Marie-Tooth disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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