
Thermo Fisher Scientific MCM7 Polyclonal Antibody
Goat 유래 다클론 항체로 인간 MCM7 단백질을 인식합니다. Western blot에 최적화되어 있으며 1:2,000–1:10,000 희석 비율로 사용 가능합니다. 액상 형태로 제공되며 4°C에서 보관합니다. 세포 복제 관련 연구용으로 적합합니다.
- 카탈로그번호
- A300128Ax (2개 옵션)
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 300 and 350 of human Minichromosome Maintenance 7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and recruitment of other DNA replication-related proteins.
The MCM complex, consisting of MCM2, 4, 6, and this protein, possesses DNA helicase activity and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase CDK4 associates with this protein and may regulate its interaction with the tumor suppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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