Thermo Fisher Scientific EXOC2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human EXOC2. Recombinant protein control fragment (Product #RP-94708). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EXOC2,uniProtId:Q96KP1-1,ncbiNodeId:9606,antigenRange:74-162,antigenLength:924,antigenImageFileName:PA5-56923_EXOC2_Q96KP1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56923_EXOC2_Q96KP1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641159

Product Specific Information

Immunogen sequence: IIVTTKSGGR GTSTVSFKLL KPEKIGILDQ SAVWVDEMNY YDMRTDRNKG IPPLSLRPAN PLGIEIEKSK FSQKDLEMLF HGMSADFTS

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 94%.

Target Information

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.