Thermo Fisher Scientific NBN Monoclonal Antibody (2C7)
인간 NBN 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western blot 및 ELISA에 적합. Affinity chromatography로 정제된 액상 형태이며 PBS buffer에 보존제 없이 제공. -20°C 보관, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2C7 |
| Immunogen | NBN (NP_002476, 645–754 a.a) partial recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
DDSEMLPKKL LLTEFRSLVI KNSTSRNPSG INDDYGQLKN FKKFKKVTYP GAGKLPHIIG GSDLIAHHAR KNTELEEWLR QEMEVQNQHA KEESLADDLF RYNPYLKRRR
Target Information
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex.
This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity.
It reveals a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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