Thermo Fisher Scientific MCRS1 Polyclonal Antibody
MCRS1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat 반응성이 있으며, 고순도 Affinity Chromatography로 정제되었습니다. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다.
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Thermo Fisher Scientific MCRS1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:1,000–1:3,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MCRS1 (Accession Q96EZ8), corresponding to amino acid residues M1–S48 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852442 |
Product Specific Information
Antibody detects endogenous levels of total MCRS1.
Target Information
MCRS1 modulates transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex, it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852).
It is a putative regulatory component of the chromatin remodeling INO80 complex, which is involved in transcriptional regulation, DNA replication, and DNA repair.
May also act as an inhibitor of TERT telomerase activity (PubMed:15044100).
Binds to G-quadruplex structures in mRNA and to RNA homopolymers poly(G) and poly(U) (PubMed:16571602). [UniProt]
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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