Thermo Fisher Scientific CYP2B6 Monoclonal Antibody (OTI3D5), TrueMAB
CYP2B6 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, IHC, ICC, Flow Cytometry에 적합합니다. 인간, 마우스, 랫트, 개 시료에 반응하며, 고순도 Affinity chromatography로 정제되었습니다. 연구용으로 약물 대사 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D5 |
| Immunogen | Full length human recombinant protein of human CYP2B6 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CYP2B6 gene encodes a member of the cytochrome P450 superfamily of enzymes. Cytochrome P450 proteins are monooxygenases that catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme metabolizes xenobiotics such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants have been described, though it remains unclear whether they originate from CYP2B6 or the closely related pseudogene CYP2B7. Both genes are located within a large cluster of cytochrome P450 genes on chromosome 19q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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