Thermo Fisher Scientific HCFC1 Polyclonal Antibody
HCFC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot과 IHC(Paraffin) 분석에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 50% 글리세롤 용액에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50–1:400 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Host Cell Factor C1 (amino acids 52–258 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.81 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903698 |
Target Information
Tumor necrosis factor (TNF) receptor associated factors (TRAFs) are adaptor proteins linking the TNF receptor superfamily to signaling pathways, playing key roles in regulating cell death and stress responses. TRAF proteins share a conserved region enabling interactions with cell receptors and other TRAF proteins, activating various signal cascades depending on the TRAFs involved. For instance, TRAF2 and TRAF3 bind to CD40, a member of the NF receptor superfamily, and are essential for NF-kappa-B activation in mouse B lymphocytes. TRAF2 and TRAF6 are required for CD40 signaling in non-hematopoietic cells. TRAF2 also interacts with the lymphotoxin-beta receptor (LTbetaR) along with TRAF3 and apoptosis inhibitors cIAP1 and Smac.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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