Thermo Fisher Scientific MAPK13 Monoclonal Antibody (OTI2G1), TrueMAB
MAPK13 단백질을 인식하는 Mouse monoclonal antibody로, WB 및 ICC/IF에 적합합니다. Human, Mouse, Rat, Dog 시료에 반응하며, Lyophilized 형태로 제공됩니다. Affinity chromatography로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G1 |
| Immunogen | Full length human recombinant protein of human MAPK13 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 100 µL distilled water to achieve ~1 mg/mL final antibody concentration.
- For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces extracellular signals such as cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by environmental stresses and proinflammatory cytokines through phosphorylation or autophosphorylation. Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, suggesting roles in stress-related transcription, cell cycle regulation, and genotoxic stress response. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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