Thermo Fisher Scientific MLPH Polyclonal Antibody
Melanophilin 단백질을 표적하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC/IF, ELISA에 적합하며 고순도 Affinity Chromatography로 정제되었습니다. 연구용으로 안정적인 신호 검출이 가능합니다.
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Thermo Fisher Scientific MLPH Polyclonal Antibody
Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 301–600 of human MLPH (NP_077006.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855376 |
Product Specific Information
Immunogen sequence:
EQLPLQYLAD VDTSDEESIR AHVMASHHSK RRGRASSESQ IFELNKHISA VECLLTYLEN TVVPPLAKGL GAGVRTEADV EEEALRRKLE ELTSNVSDQE TSSEEEEAKD EKAEPNRDKS VGPLPQADPE VGTAAHQTNR QEKSPQDPGD PVQYNRTTDE ELSELEDRVA VTASEVQQAE SEVSDIESRI AALRAAGLTV KPSGKPRRKS NLPIFLPRVA GKLGKRPEDP NADPSSEAKA MAVPYLLRRK FSNSLKSQGK DDDSFDRKSV YRGSLTQRNP NARKGMASHT FAKPVVAHQS
Target Information
Slac2-a (synaptotagmin-like protein homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes.
Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its SHD domain near the N-terminus.
Pigment and cytotoxic granule transport in melanocytes requires the stable formation of this complex. Mutations in binding domains can cause albinism or immune disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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