Thermo Fisher Scientific TNFAIP8L1 Polyclonal Antibody
TNFAIP8L1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 적용 가능. 고순도 Affinity chromatography 정제, 1 mg/mL 농도. 인간, 마우스, 랫트 반응성. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TNFAIP8L1 (Accession Q8WVP5), corresponding to amino acid residues V29–L79 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852686 |
Product Specific Information
Antibody detects endogenous levels of total TNFAIP8L1.
Target Information
Tumor necrosis factor α-induced protein 8-like 1 (TNFAIP8L1), also known as TNFα-IP 8L1, is a 186 amino acid protein belonging to the TNFα-IP 8 family.
Members of this family are induced by nuclear factor-κB (NFκB) and tumor necrosis factor (TNF), with TNF induction dependent on NFκB activation.
TNFα-IP 8 proteins act as negative mediators of apoptosis and may play roles in tumor progression. They suppress TNF-mediated apoptosis by inhibiting caspase-8 activity, preventing BID cleavage and caspase-3 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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