Thermo Fisher Scientific ITM2B Monoclonal Antibody (OTI1C11)
ITM2B 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, Flow Cytometry에 사용 가능. 인간 시료 반응성. 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관. 알츠하이머 관련 연구에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C11 |
| Immunogen | Full length human recombinant protein of ITM2B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724534 |
Target Information
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease.
This gene encodes a transmembrane protein processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide that inhibits beta-amyloid deposition.
Mutations extending the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with familial British dementia and familial Danish dementia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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