Thermo Fisher Scientific mPR gamma Polyclonal Antibody
Rabbit polyclonal antibody targeting human mPR gamma for ICC/IF applications. Recognizes recombinant human mPR gamma with high specificity. Supplied unconjugated in liquid form with 0.1 mg/mL concentration. Ideal for research use in studying membrane p...
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human mPR gamma. Recombinant protein control fragment (Product #RP-108096) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664965 |
Product Specific Information
- Immunogen sequence: RLFLFPGESAQ NEATSYHQK
- Highest antigen sequence identity to the following orthologs: mouse 80%, rat 80%
Target Information
The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase, reduces intracellular cAMP, and activates mitogen-activated protein kinase to effect signal transduction pathways.
Three distinct groups, designated alpha, beta, and gamma, comprise this gene family. While all contain 7 transmembrane domains, they show distinct distributions in reproductive, neural, kidney, and intestinal tissues. These characteristics separate them from nuclear progestin receptors and imply similarity to G-protein coupled receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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